With over three decades of research, product development, and executive leadership experience in healthcare, tech industry, and academic medicine, Dr. Stephen Wong currently serves the John S. Dunn Presidential Distinguished Endowed Chair in Biomedical Engineering and the Founding Chair of Systems Medicine and Bioengineering Department at Houston Methodist Hospital.  His expansive roles include Directorship of the T.T. & W.F. Chao Center for BRAIN, the Artificial Intelligence in Medicine and Innovation Laboratory, and the Translational Biophotonics Laboratory, along with being the Associate Director for Shared Resources at Houston Methodist Neal Cancer Center and Chief Research Information Officer at Houston Methodist Hospital. Wong is also a Professor of Radiology, Pathology, Neurosciences, and Laboratory Medicine at Cornell University and adjunct professorships at several notable institutions, including MD Anderson Cancer Center, Baylor College of Medicine, Rice University, the University of Texas Health Sciences Center at Houston, Texas A&M University, the University of Texas Health Sciences Center, and the University of Houston. His previous professorial positions were at Harvard University and the UCSF School of Medicine.

Dr. Wong is recognized for pioneering the field of medical image informatics in the early 1990s, notably developing the world’s first custom-built, hospital-wide Picture Archiving and Communication System (PACS) at UCSF. This revolutionary system significantly transformed the practices of medical imaging management and radiology, paving the way for what has now become a multi-billion dollar industry. He continued his innovations at Philips Healthcare as the Chief Architect and Department Head of Integrated Clinical Product Development, where he led the development of Europe's most extensive radiology information management system and the first object-oriented electronic medical record system. 

At Harvard Medical School, Dr. Wong established the Harvard Center for Neurodegeneration and Repair Bioinformatics Research Center, integrating machine learning and systems biology with high throughput and high content cellular screening for drug discovery. He also founded the Functional and Molecular Imaging Center at Brigham and Women’s Hospital, which included the implementation of their inaugural cyclotron and the MRI/CT/PET research imaging core facilities. His tenure at Houston Methodist saw the creation of an enterprise-wide clinical data warehouse, an AI in Medicine Program, the Translational Biophotonics Laboratory, the Advanced Cellular and Tissue Microscopy Core, the Cancer Center Shared Resources, and the Translational Imaging Center, significantly enhancing the institution's research and treatment capabilities.

His research at Houston Methodist has led to several clinical trials in the United States, including breast and brain cancer drug repositioning, breast cancer screening and diagnosis, image-guided lung cancer therapy, digital cancer therapeutics, and AI augmented stroke triage and detection. 

In addition to his contributions to healthcare and life sciences, he has held influential roles in the corporate sector, including as the Vice President at Charles Schwab during the height of the dot-com era, where he was instrumental in developing the world's largest web trading platform at the time, catering to 9 million customers globally. Dr. Wong's expertise also extended to his tenure at AT&T Bell Labs, where he played a crucial role in the research and development of very large-scale integration (VLSI) computer chips, focusing on innovative design and the automation of production processes.

As a recognized global thought leader, Wong serves on several advisory boards of medical institutions and disease Foundations, both in the United States and internationally.  He is a sought-after speaker, sharing his insights on a myriad of subjects such as AI, medical imaging, bioinformatics, data science, digital health, systems biology, drug repositioning, and the crucial aspects of data security and privacy in healthcare. His talks also address the intricate molecular mechanisms underlying various cancers and neurodegenerative diseases.

Wong is a Fellow in several prestigious organizations, including Institute of Electrical and Electronics Engineers (IEEE), American Institute for Medical and Biological Engineering (AIMBE), American College of Medical Informatics (ACMI), American Medical Informatics Association (AMIA), The International Academy of Medical and Biological Engineering (IAMBE), Optica (formerly Optical Society of America), and Asia-Pacific Artificial Intelligence Association (AAIA), underscoring his contributions to multiple scientific disciplines. Additionally, he is a licensed Professional Engineer (PE) in the United States. 

Wong received a B.Eng. in Electrical Engineering, awarded with honors from the University of Western Australia in Perth, followed by an M.Sc. and a Ph.D. in Computer Science, specializing in Artificial Intelligence, from Lehigh University in Bethlehem, Pennsylvania. Further enriching his expertise, Wong completed a postdoctoral fellowship at the renowned Japanese Fifth Generation Computer Systems Project (ICOT) in Tokyo, focused on research in massive parallel and deductive AI. He also expanded his leadership skills through senior executive programs at Stanford University, MIT, and Columbia University.

Wong's teaching career has spanned several prestigious universities, including Harvard, UCSF, UC Berkeley, Stanford, and currently includes appointments at Cornell University, Texas A&M University, MD Anderson Cancer Center, and Rice University and his research has been consistently funded by the NIH for over thirty years. He has mentored over 170 Ph.D. and postdoctoral researchers and authored over 500 scientific papers. As of January 2024, his Google Scholar citations number 27,292 with an H-index of 75.Dr. Wong's early years in Hong Kong and a gap year backpacking in the Philippines reflect his diverse and global career trajectory, having worked in multiple international cities. He has lived and worked in Perth, Canberra, Singapore, Orlando, Tokyo, Amsterdam, San Francisco, Silicon Valley, and Boston, with his current home being in Houston. Having transitioned from the corporate sector to academic medicine, he continues to address complex challenges in healthcare and diseases, particularly in cancer and neurological disorders.